Neuroendocrine tumors of the stomach: chemotherapy with cisplatin plus irinotecan is effective for gastric poorly-differentiated neuroendocrine carcinoma
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چکیده
منابع مشابه
Feasibility and efficacy of combined cisplatin and irinotecan chemotherapy for poorly differentiated neuroendocrine carcinomas.
OBJECTIVE No standard treatment has been established for poorly differentiated neuroendocrine carcinoma; the usual recommended treatment is based on the strategy for small cell lung carcinoma. The aim of this study was to evaluate the response of poorly differentiated neuroendocrine carcinoma to the combination of irinotecan and cisplatin in one institution. METHODS We retrospectively reviewe...
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Gastric neuroendocrine carcinoma is a rare tumor which has a poor prognosis. Herein, we present a 55-year-old woman who presented with complaints of recurrent vomiting, hematemesis and weight loss. Endoscopic examination showed a large ulcerated mass in the antrum. Microscopic evaluation of the specimen taken through biopsy was compatible with a small round cell tumor. However, definitive histo...
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Anatomo-clinical studies of the neuroendocrine tumors of the stomach only can be well completed with a view of the basic characteristics of the elements of the so-called neuroendocrine system or gastrointestinal APUD system. Therefore, these gastric neoplasias cannot be studied in isolation because they are derived from a special line of endocrine cells that have many common biochemical bonds w...
متن کاملCisplatin and etoposide as first-line chemotherapy for poorly differentiated neuroendocrine carcinoma of the hepatobiliary tract and pancreas.
OBJECTIVE The combination chemotherapy consisting of cisplatin and etoposide, one of the standard regimens for small cell lung cancer, has been widely used to treat extrapulmonary poorly differentiated neuroendocrine carcinomas. However, there were no prior reports limited to the hepatobiliary tract and pancreas as the primary sites. METHODS We reviewed the cases in our database from October ...
متن کاملTreatment of poorly differentiated neuroendocrine carcinoma of the pancreas.
Poorly differentiated neuroendocrine carcinoma is a rare malignancy that remains a challenge to treat. Poorly differentiated neuroendocrine carcinoma occurs at an incidence of 2% annually in United States. The current standard of care is based largely upon retrospective data. There remains a need for large prospective cooperative group trials in the management of poorly differentiated neuroendo...
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ژورنال
عنوان ژورنال: Gastric Cancer
سال: 2011
ISSN: 1436-3291,1436-3305
DOI: 10.1007/s10120-011-0025-5